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KMID : 0359920100290050650
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Korean Journal of Nephrology
2010 Volume.29 No. 5 p.650 ~ p.655
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A Case of Recurrent C1q Nephropathy Treated by Immunosuppressant Combination Therapy
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Park Min-Bom
Kim Eun-Na
Jeong Eun-Ho
Kim Jin-Ou
Wang Hee-Bae
Kim Tae-Ho
Lee Key-Jo
Suh Sang-Yeol
Jin So-Young
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Abstract
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The definition of C1q nephropathy has been categorized since 1985. However, the clinical correlation and pathophysiology has not yet been fully revealed. Therefore, the treatment of C1q nephropathy has not been established. Our subject was a 23 year-old female patient with both leg edema and oliguria, who was presented with weight gain. Renal biopsy confirmed C1q nephropathy. Prednisolone and cyclosporine therapy was selected for treatment. After 2 weeks of treatment, the patient lost 8 kg of body weight and all laboratory examination results were normalized. Both leg edema and oliguria were resolved. After 21 weeks of regular follow-up, she stopped the medicine by herself. Eight weeks later, the patient came to the Emergency room because both leg edema recurred. Same regimen was administered for 3 weeks, and complete remission was achieved again.
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KEYWORD
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C1q, Prednisolone, Cyclosporine
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